Tibolone mechanism
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Postmenopausal Tibolone Therapy: Biologic Principles and Applied ...2007年1月3日 · Tibolone, an analogue of the progestin, norethynodrel, is a drug with ... nongenomic membrane receptor and even an estrogen-independent mechanism . ... Rubin GL, Harrold AJ, Mills JA, et al. ... Twitter; Share on Google Plus ...Tissue-selectivity: the mechanism of action of tibolone - PubMedTibolone is effective in preventing bone loss and treating climacteric symptoms, without stimulating the endometrium. The effects on bone, brain and vagina can ...Endometrial Effects of Tibolone | The Journal of Clinical ...Background and Objectives: The Tibolone Histology of the Endometrium and ... the following two mechanisms: tibolone deactivates estrogenic compounds and ...The Effects of Tibolone in Older Postmenopausal Women | NEJM2008年8月14日 · Background Tibolone has estrogenic, progestogenic, and androgenic effects. Although tibolone prevents bone loss, its effects on fractures, ...Effects of hormone therapy and tibolone on body composition and ...Key Words: Hormone therapy, tibolone, leptin, body composition. Several ... administration may help to reverse this mechanism (7). Tibo- lone is a ... Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, ... Tyndall GL, et al.Comparison of Tibolone and Conjugated Equine ... - AHA Journalscommon or internal carotid artery atherosclerosis and to evaluate tibolone treatment relative to conjugated equine estrogens ... of the lower HDLC could be a result of the mechanism by ... Manolio TA, Burke GL, O'Leary DH, Evans G, Beauchamp N, Knepper ... Thompson SG, Meade TW, Greenberg G. The use of hormonal.Comparison of Tibolone and Conjugated Equine Estrogens Effects ...2002年11月1日 · It is possible that by similar mechanisms, the 3-α and 3-β hydroxy estrogenic metabolites of tibolone are acting directly on the artery wall to ...The synthetic steroid tibolone exerts sex-specific regulation of ...2020年1月28日 · Then, the effect of tibolone on the phagocytosis of Cy3-conjugated cellular debris was ... Thus, the mechanisms of tibolone action in male neural cells remain unexplored. Previous ... Jung-Testas I, Renoir M, Bugnard H, Greene GL, Baulieu EE. ... BMC Twitter page · BMC Facebook page · BMC Weibo page.Tibolone - WikipediaTibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of ...Cardiovascular Effects of Tibolone: A Selective Tissue Estrogenic ...2007年7月3日 · Email; Facebook; Twitter; Linked In; Reddit; Wechat ... Tibolone is a synthetic compound with estrogenic, androgenic, and progestogenic ... Tibolone possesses a tissue‐selective mechanism of action that differs from that ... Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, ...
延伸文章資訊
- 1Tibolone - Maturitas
Tibolone: how does its mechanism of action translate into clinical effects. Peter Kenemans. Depar...
- 2Beneficial effect of tibolone on mood, cognition, well-being, and ...
- 3E25. The tissue-selective mechanism of action of ... - CORE
Tibolone expresses tissue-specific oestrogenic activity. Oestrogenic effects are seen on thermo-r...
- 4Tibolone | DrugBank Online
In breast tissue, the primary actions of tibolone are strong inhibition of sulfatase activity and...
- 5Tissue-selectivity: The mechanism of action of tibolone ...
The tissue-selective effects of tibolone are the result of metabolism, enzyme regulation and rece...